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Nfkbiz Gene Detail
 Symbol
Name
ID
Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
MGI:1931595


Nomenclature History
Synonyms Mail
Genetic Map
Chromosome 16
cytoband C1.2 - C1.3
 
Mapping data( 3)
Sequence Map
Chr16:55811488-55839012 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF330224
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000019996 VEGA Gene Model | MGI Sequence Detail 27525 C57BL/6J ± Kb
transcript NM_030612 RefSeq | MGI Sequence Detail 3855 C57BL/6
polypeptide Q9EST8 UniProt | EBI | MGI Sequence Detail 728 Not Applicable
For the selected sequences
All sequences(48)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(2)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)   Phenotype Images (2)  
Polymorphisms SNPs within 2kb(86 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process inflammatory response, regulation of transcription...
Component nucleus
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (3)    Results (48)    Tissues (46)    Images (3)
Theiler Stages: 2,3,4,5,17,18,21,28
  Assay Type Assays   Results
      RT-PCR 1   15
      RNA in situ 2   33
cDNA source data(64)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(65) cDNA(64) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000035356
DoTS DT.101397233, DT.101703302, DT.110728278, DT.110728290, DT.40143733, DT.489262
Consensus CDS Project CCDS28216.1
UniGene 247272
DFCI TC1576131, TC1595439, TC1621411, TC1679370
NIA Mouse Gene Index U037110
Entrez Gene 80859
VEGA Gene Model OTTMUSG00000019996
International Mouse Knockout Project Status Nfkbiz
Protein
domains
InterPro ID Description
IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
Graphical View of Protein Domain Structure
References
(Earliest) J:65974 Kitamura H et al., "MAIL, a novel nuclear IkappaB protein that potentiates LPS-induced IL-6 production" FEBS Lett 2000 Nov 17;485(1):53-6
(Latest) J:141704 Ueta M et al., "Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta-/- mice." Invest Ophthalmol Vis Sci 2008 Aug;49(8):3387-94
All references(16)
Other
accession IDs
MGI:2146337

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory