Symbol
Name
ID
|
|
|
Synonyms
|
1200016O07Rik, alpha 1 sGC
|
|
Genetic Map
|
|
Chromosome 3
|
Syntenic
|
|
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Mapping data(
5)
|
|
|
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Sequence Map
|
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Mammalian
homology
|
|
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Sequences
|
All sequences(21)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, knock-out(2)
Targeted, other(1)
| Mice homozygous for a null mutation display mild elevation of systolic blood pressure, and abnormal blood vessel and platelet responses to NO. |
|
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Polymorphisms
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SNPs within 2kb(340 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (2 records)
Data Summary:
Assays (2)
Results (95)
Tissues (95)
Images (21)
Theiler Stages: 20,22
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
2 |
| |
RNA in situ |
1 |
|
93 |
cDNA source data(8)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(13)
Genomic(1)
cDNA(10)
Primer pair(2)
Microarray probesets(3)
|
|
Pathways
|
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR001054 |
Adenylyl cyclase class-3/4/guanylyl cyclase |
| IPR011644 |
Haem NO binding |
| IPR011645 |
Haem NO binding associated |
| IPR018297 |
Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:64709
Sharina IG et al.,
"Genomic organization of alpha 1 and beta 1 subunits of the mammalian soluble guanylyl cyclase genes"
Proc Natl Acad Sci U S A 2000 Sep 26;97(20):10878-83
(Latest)
J:155687
Cauwels A et al.,
"Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase-dependent manner."
J Exp Med 2009 Dec 21;206(13):2915-24
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All references(19)
|
Other
accession IDs
|
MGI:1921380
|
Analysis Tools
MGI BioMart