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Trat1 Gene Detail
 Symbol
Name
ID
Trat1
T cell receptor associated transmembrane adaptor 1
MGI:1924897

Nomenclature History
Synonyms C030046M14Rik, Tcrim, Trim
Genetic Map
Chromosome 16
Syntenic
 
Mapping data( 1)
Sequence Map
Chr16:48732023-48772248 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF336066
Sequences
Representative Sequences Length Strain/Species Flank
genomic 77647 NCBI Gene Model | MGI Sequence Detail 40226 C57BL/6J ± Kb
transcript NM_198297 RefSeq | MGI Sequence Detail 684 -
polypeptide Q3UU67 UniProt | EBI | MGI Sequence Detail 187 Not Applicable
For the selected sequences
All sequences(18)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Mice with homozygous disruption of this gene display decreased body weight and a proportional reduction in lymph organ cell numbers; however T and B cell function are normal.
Polymorphisms SNPs within 2kb(254 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process immune response, negative regulation of receptor recycling...
Component integral to membrane, membrane...
External Resources: FuncBase
Expression cDNA source data(14)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(14) cDNA(14)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030775
DoTS DT.101318411, DT.40163783
Consensus CDS Project CCDS37352.1
UniGene 167298
DFCI TC1588950, TC1597730
NIA Mouse Gene Index U037089
Entrez Gene 77647
International Mouse Knockout Project Status Trat1
Protein
domains
InterPro ID Description
IPR020399 T-cell receptor-associated transmembrane adapter 1
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J et al., "Functional annotation of a full-length mouse cDNA collection." Nature 2001 Feb 8;409(6821):685-90
(Latest) J:140748 Koelsch U et al., "SIT and TRIM determine T cell fate in the thymus." J Immunol 2008 Nov 1;181(9):5930-9
All references(6)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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