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Smpdl3b Gene Detail
 Symbol
Name
ID
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
MGI:1916022

Nomenclature History
Synonyms 1110054A24Rik, Asml3b
Genetic Map
Chromosome 4
Syntenic
 
Mapping data( 2)
Sequence Map
Chr4:132288881-132313167 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: acid sphingomyelinase-like phosphodiesterase
TreeFam: TF313674
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000009962 VEGA Gene Model | MGI Sequence Detail 24287 C57BL/6J ± Kb
transcript NM_133888 RefSeq | MGI Sequence Detail 1925 C57BL/6
polypeptide P58242 UniProt | EBI | MGI Sequence Detail 456 Not Applicable
For the selected sequences
All sequences(23)
Alleles
and
phenotypes 		All alleles(50) : Gene trapped(50)
Polymorphisms SNPs within 2kb(176 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process metabolic process, sphingomyelin catabolic process...
Component extracellular region, extracellular space...
Function hydrolase activity, hydrolase activity, acting on glycosyl bonds...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (94)    Tissues (94)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   94
cDNA source data(28)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(30) Genomic(1) cDNA(28) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000028885
DoTS DT.526579, DT.97370592, DT.97410241
Consensus CDS Project CCDS18733.1
UniGene 287187
DFCI TC1579618
NIA Mouse Gene Index U025607
Entrez Gene 100340
VEGA Gene Model OTTMUSG00000009962
International Mouse Knockout Project Status Smpdl3b
Protein
domains
InterPro ID Description
IPR004843 Metallophosphoesterase
IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS et al., "Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development." Development 2000 Apr;127(8):1737-49
(Latest) J:154029 Munger SC et al., "Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal." Genes Dev 2009 Nov 1;23(21):2521-36
All references(8)
Other
accession IDs 		MGI:2140498
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory