About   Help   FAQ
Ctnnbip1 Gene Detail
 Symbol
Name
ID
Ctnnbip1
catenin beta interacting protein 1
MGI:1915756


Nomenclature History
Synonyms 1110008O09Rik, 2310001I19Rik, Catnbip1, ICAT
Genetic Map
Chromosome 4
Syntenic
 
Mapping data( 2)
Sequence Map
Chr4:148892345-148940546 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; rat    (Mammalian Orthology)
TreeFam: TF314533
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000010278 VEGA Gene Model | MGI Sequence Detail 48202 C57BL/6J ± Kb
transcript NM_023465 RefSeq | MGI Sequence Detail 2686 C57BL/6
polypeptide Q9JJN6 UniProt | EBI | MGI Sequence Detail 81 Not Applicable
For the selected sequences
All sequences(26)
Alleles
and
phenotypes
All alleles(11) : Targeted, knock-out(1) Gene trapped(10)
Homozygous null mice display neonatal lethality associated with rupture of the gut, posteriorized neural cell fate within the neural plate, and abnormal craniofacial morphology.
Phenotype Images (2)  
Polymorphisms SNPs within 2kb(311 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process anterior/posterior pattern formation, negative regulation of transcription from RNA polymerase II promoter...
Component cytoplasm, nucleus...
Function beta-catenin binding, protein binding...
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Assays (1)    Results (19)    Tissues (19)
Theiler Stages: 17,19,20,21,22
  Assay Type Assays   Results
      Immunohistochemistry 1   19
cDNA source data(9)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(9) cDNA(9) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000028988
DoTS DT.534249, DT.97371321
Consensus CDS Project CCDS38975.1
DFCI TC1576409, TC1590957
Entrez Gene 67087
VEGA Gene Model OTTMUSG00000010278
International Mouse Knockout Project Status Ctnnbip1
Protein
domains
InterPro ID Description
IPR009428 Beta-catenin-interacting ICAT
Graphical View of Protein Domain Structure
References
(Earliest) J:74520 Tago K et al., "Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein." Genes Dev 2000 Jul 15;14(14):1741-9
(Latest) J:125187 Hasegawa Y et al., "Loss of ICAT gene function leads to arrest of ureteric bud branching and renal agenesis." Biochem Biophys Res Commun 2007 Nov 3;362(4):988-94
All references(12)
Other
accession IDs
MGI:1914337, MGI:2140573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/06/2010
MGI_4.32
Web browser compatibility
The Jackson Laboratory