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Lin28 Gene Detail
 Symbol
Name
ID
Lin28
lin-28 homolog (C. elegans)
MGI:1890546

Nomenclature History
Synonyms Lin-28, Lin28a, Tex17
Genetic Map
Chromosome 4
Syntenic
 
Mapping data( 2)
Sequence Map
Chr4:133559245-133574756 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF316240
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000010211 VEGA Gene Model | MGI Sequence Detail 15512 C57BL/6J ± Kb
transcript NM_145833 RefSeq | MGI Sequence Detail 3480 -
polypeptide Q8K3Y3 UniProt | EBI | MGI Sequence Detail 209 Not Applicable
For the selected sequences
All sequences(15)
Alleles
and
phenotypes 		All alleles(46) : Gene trapped(46)
Polymorphisms SNPs within 2kb(78 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process gene silencing by RNA, miRNA catabolic process...
Component cytoplasm, nucleolus...
Function DNA binding, metal ion binding...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression Literature Summary: (7 records)
Data Summary: Assays (5)    Results (63)    Tissues (58)    Images (25)
Theiler Stages: 1,2,3,4,5,9,11,13,15,17,20,23,25,28
  Assay Type Assays   Results
      Western blot 1   5
      RT-PCR 1   12
      RNA in situ 1   2
      Immunohistochemistry 2   44
cDNA source data(22)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(24) cDNA(22) Primer pair(2) Antibodies(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000050966
Consensus CDS Project CCDS18761.1
UniGene 302567
Entrez Gene 83557
VEGA Gene Model OTTMUSG00000010211
International Mouse Knockout Project Status Lin28
Protein
domains
InterPro ID Description
IPR001878 Zinc finger, CCHC-type
IPR002059 Cold-shock protein, DNA-binding
IPR011129 Cold shock protein
IPR012340 Nucleic acid-binding, OB-fold
IPR013084 Zinc finger, CCHC retroviral-type
IPR016027 Nucleic acid-binding, OB-fold-like
Graphical View of Protein Domain Structure
References
(Earliest) J:68614 Wang PJ et al., "An abundance of X-linked genes expressed in spermatogonia." Nat Genet 2001 Apr;27(4):422-6
(Latest) J:150963 Pavlinkova G et al., "Maternal diabetes alters transcriptional programs in the developing embryo." BMC Genomics 2009;10():274
All references(12)
Other
accession IDs 		MGI:2140415
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory