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Pde7b Gene Detail
 Symbol
Name
ID
Pde7b
phosphodiesterase 7B
MGI:1352752


Nomenclature History
Genetic Map
Chromosome 10
cytoband A3
 
Mapping data( 2)
Sequence Map
Chr10:20117810-20444884 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF314638
Sequences
Representative Sequences Length Strain/Species Flank
genomic 29863 NCBI Gene Model | MGI Sequence Detail 327075 C57BL/6J ± Kb
transcript NM_013875 RefSeq | MGI Sequence Detail 4127 C57BL/6
polypeptide Q9QXQ1 UniProt | EBI | MGI Sequence Detail 446 Not Applicable
For the selected sequences
All sequences(17)
Alleles
and
phenotypes
All alleles(2) : Targeted, other(2)
Polymorphisms SNPs within 2kb(1380 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process signal transduction
Function 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (2)    Results (12)    Tissues (12)
Theiler Stages: 13,17,21,23,28
  Assay Type Assays   Results
      Northern blot 2   12
cDNA source data(5)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(3)
Other database
links
EC 3.1.4.17
Ensembl Gene Model ENSMUSG00000019990
Consensus CDS Project CCDS35859.1
DFCI TC1585644, TC1694293
NIA Mouse Gene Index U031592
Entrez Gene 29863
International Mouse Knockout Project Status Pde7b
Protein
domains
InterPro ID Description
IPR002073 3'5'-cyclic nucleotide phosphodiesterase
IPR003607 Metal-dependent phosphohydrolase, HD domain
Graphical View of Protein Domain Structure
References
(Earliest) J:59365 Hetman JM et al., "Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase." Proc Natl Acad Sci U S A 2000 Jan 4;97(1):472-6
(Latest) J:133670 Omori K et al., "Overview of PDEs and their regulation." Circ Res 2007 Feb 16;100(3):309-27
All references(7)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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