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Trpm2 Gene Detail
 Symbol
Name
ID
Trpm2
transient receptor potential cation channel, subfamily M, member 2
MGI:1351901

Nomenclature History
Synonyms 9830168K16Rik, LTRPC2, TRPC7, Trrp7
Genetic Map
Chromosome 10
41.7 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr10:77370467-77433308 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Trpm2 ± 2 cM)
Protein SuperFamily: transient receptor potential cation channel TRPM2
TreeFam: TF314204
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000020526 VEGA Gene Model | MGI Sequence Detail 62842 C57BL/6J ± Kb
transcript NM_138301 RefSeq | MGI Sequence Detail 7292 C57BL/6
polypeptide Q91YD4 UniProt | EBI | MGI Sequence Detail 1507 Not Applicable
For the selected sequences
All sequences(36)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Gene trapped(1)
Polymorphisms SNPs within 2kb(221 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process calcium ion transport, ion transport...
Component integral to membrane, membrane...
Function ADP-ribose diphosphatase activity, calcium channel activity...
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Assays (4)    Results (66)    Tissues (64)    Images (4)
Theiler Stages: 13,15,17,20,22,23,26,28
  Assay Type Assays   Results
      RT-PCR 2   18
      RNA in situ 2   48
cDNA source data(12)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(24) Genomic(10) cDNA(12) Primer pair(2)
Microarray probesets(1)
Other database
links
EC 3.6.1.13
Ensembl Gene Model ENSMUSG00000009292
DoTS DT.101366575, DT.110614907, DT.110614917, DT.40154367, DT.522478, DT.55129416, DT.91358579, DT.94251906
UniGene 276762
DFCI TC1583705, TC1615939, TC1617858, TC1623060, TC1693762
NIA Mouse Gene Index U031963
Entrez Gene 28240
VEGA Gene Model OTTMUSG00000020526
International Mouse Knockout Project Status Trpm2
Protein
domains
InterPro ID Description
IPR005821 Ion transport
IPR015797 NUDIX hydrolase domain-like
Graphical View of Protein Domain Structure
References
(Earliest) J:59327 Wiltshire T et al., "Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21." Genome Res 1999 Dec;9(12):1214-22
(Latest) J:148796 Lechner SG et al., "Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development." EMBO J 2009 May 20;28(10):1479-91
All references(14)
Other
accession IDs 		MGI:2143924, MGI:2444747
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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