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Pla2g7 Gene Detail
 Symbol
Name
ID
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
MGI:1351327

Nomenclature History
Synonyms PAF acetylhydrolase
Genetic Map
Chromosome 17
cytoband C
 
Mapping data( 4)
Sequence Map
Chr17:43705218-43749150 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: PAF acetylhydrolase
TreeFam: TF313831
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000026307 VEGA Gene Model | MGI Sequence Detail 43933 C57BL/6J ± Kb
transcript NM_013737 RefSeq | MGI Sequence Detail 1923 C57BL/6
polypeptide Q60963 UniProt | EBI | MGI Sequence Detail 440 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes 		All alleles(2) : Targeted, other(2)
Polymorphisms SNPs within 2kb(335 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process inflammatory response, lipid catabolic process...
Component extracellular region
Function 1-alkyl-2-acetylglycerophosphocholine esterase activity, hydrolase activity...
External Resources: FuncBase
Expression Literature Summary: (3 records)
Data Summary: Assays (4)    Results (125)    Tissues (117)    Images (15)
Theiler Stages: 11,13,19,22,28
  Assay Type Assays   Results
      RT-PCR 2   29
      RNA in situ 2   96
cDNA source data(11)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(2)
Other database
links
EC 3.1.1.47
Ensembl Gene Model ENSMUSG00000023913
DoTS DT.101399886, DT.489494, DT.94181217
Consensus CDS Project CCDS28796.1
DFCI TC1575197, TC1595303, TC1663272
NIA Mouse Gene Index U018006
Entrez Gene 27226
VEGA Gene Model OTTMUSG00000026307
International Mouse Knockout Project Status Pla2g7
Protein
domains
InterPro ID Description
IPR005065 Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II
IPR016715 PAF acetylhydrolase
Graphical View of Protein Domain Structure
References
(Earliest) J:29539 Tjoelker LW et al., "Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad." J Biol Chem 1995 Oct 27;270(43):25481-7
(Latest) J:147173 Sultana DA et al., "Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development." Blood 2009 Mar 26;113(13):2976-87
All references(10)
Other
accession IDs 		MGI:2147157
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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