Symbol
Name
ID
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Synonyms
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ABC39, adrenoleukodystrophy related, ALDL1, ALDR
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Genetic Map
|
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Chromosome 15
|
cytoband E-F
|
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Mapping data(
2)
|
|
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(26)
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Alleles
and
phenotypes
|
All alleles(1) :
Targeted, knock-out(1)
| Mice homozygous for a disruption in this gene exhibit a late-onset cerebellar and sensory ataxia, loss of Purkinje cells, dorsal root ganglia cell degeneration, axonal degeneration in the spinal cord, and an accumulation of very long chain fatty acids. |
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Polymorphisms
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SNPs within 2kb(294 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (2 records)
Data Summary:
Assays (8)
Results (28)
Tissues (13)
Theiler Stages: 20,22,26,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
4 |
| |
Northern blot |
7 |
|
24 |
cDNA source data(42)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(45)
Genomic(2)
cDNA(42)
Primer pair(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:41547
Lombard-Platet G et al.,
"A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern."
Proc Natl Acad Sci U S A 1996 Feb 6;93(3):1265-9
(Latest)
J:146101
Singh J et al.,
"Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy."
J Lipid Res 2009 Jan;50(1):135-47
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All references(18)
|
Analysis Tools
MGI BioMart