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Sdc4 Gene Detail
 Symbol
Name
ID
Sdc4
syndecan 4
MGI:1349164


Nomenclature History
Synonyms ryudocan, Synd4, syndecan-4
Genetic Map
Chromosome 2
94.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr2:164249747-164269387 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Sdc4 ± 2 cM)
Protein SuperFamily: ryudocan
TreeFam: TF320463
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000001157 VEGA Gene Model | MGI Sequence Detail 19641 C57BL/6J ± Kb
transcript NM_011521 RefSeq | MGI Sequence Detail 2460 C57BL/6
polypeptide O35988 UniProt | EBI | MGI Sequence Detail 198 Not Applicable
For the selected sequences
All sequences(30)
Alleles
and
phenotypes
All alleles(24) : Targeted, knock-out(2) Targeted, other(1) Gene trapped(21)
Mice homozygous or heterozygous for a targeted mutation display statistically significant delayed healing of skin wounds and impaired angiogenesis in the granulation tissue.
Polymorphisms RFLP(1) SNPs within 2kb(147 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component cell surface, integral to membrane...
Function cytoskeletal protein binding
External Resources: FuncBase
Expression Literature Summary: (12 records)
Data Summary: Assays (5)    Results (13)    Tissues (13)    Images (6)
Theiler Stages: 3,4,5,16,17,28
  Assay Type Assays   Results
      RT-PCR 2   8
      Immunohistochemistry 2   4
      Northern blot 1   1
cDNA source data(13)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(2) Antibodies(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000017009
DoTS DT.87069462, DT.94350098, DT.97413294, DT.99848354
Consensus CDS Project CCDS17036.1
DFCI TC1574558, TC1596910
NIA Mouse Gene Index U023635
Entrez Gene 20971
VEGA Gene Model OTTMUSG00000001157
International Mouse Knockout Project Status Sdc4
Protein
domains
InterPro ID Description
IPR001050 Syndecan
IPR003585 Neurexin/syndecan/glycophorin C
Graphical View of Protein Domain Structure
References
(Earliest) J:23985 Baciu PC et al., "Prediction of a novel integral membrane proteoglycan core protein related to Syndecan and Fibroglycan" J Cell Biol 1991;115():125a
(Latest) J:154621 Stanford KI et al., "Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice." J Clin Invest 2009 Nov;119(11):3236-45
All references(48)
Other
accession IDs
MGD-MRK-14689, MGI:2138809, MGI:2139303, MGI:98466

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory