Symbol
Name
ID
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Synonyms
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1110058H21Rik, UBP43
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(27)
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Alleles
and
phenotypes
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All alleles(2) :
Targeted, other(1)
Gene trapped(1)
| Homozygous null mutants die prematurely and show cellular necrosis in ependyma and breakdown of blood-brain barrier, hydrocephaly with enlarged ventricles and severe neurological abnormalities including convulsions, tremor, ataxia, rolling, and circling. |
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Polymorphisms
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SNPs within 2kb(101 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (2 records)
cDNA source data(47)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(48)
cDNA(47)
Other(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR001394 |
Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 |
| IPR018200 |
Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:53884
Liu LQ et al.,
"A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation."
Mol Cell Biol 1999 Apr;19(4):3029-38
(Latest)
J:152613
Sarasin-Filipowicz M et al.,
"Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43."
Mol Cell Biol 2009 Sep;29(17):4841-51
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All references(17)
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Other
accession IDs
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MGI:1916032, MGI:2141633
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Analysis Tools
MGI BioMart
