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Klf1 Gene Detail
 Symbol
Name
ID
Klf1
Kruppel-like factor 1 (erythroid)
MGI:1342771


Nomenclature History
Synonyms Eklf
Genetic Map
Chromosome 8
38.6 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr8:87425827-87429184 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Klf1 ± 2 cM)
TreeFam: TF315506
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000054191 Ensembl Gene Model | MGI Sequence Detail 3358 C57BL/6J ± Kb
transcript NM_010635 RefSeq | MGI Sequence Detail 1534 -
polypeptide P46099 UniProt | EBI | MGI Sequence Detail 358 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes
All alleles(13) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(11)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms RFLP(1) SNPs within 2kb(38 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process chromatin remodeling, embryonic hemopoiesis...
Component intracellular, nucleus...
Function DNA binding, metal ion binding...
External Resources: FuncBase
Expression Literature Summary: (20 records)
Data Summary: Assays (10)    Results (41)    Tissues (24)    Images (7)
Theiler Stages: 10,12,14,15,16,17,18,19,20,21,22,23,25,28
  Assay Type Assays   Results
      Western blot 2   7
      RT-PCR 4   15
      RNA in situ 1   4
      Northern blot 3   15
cDNA source data(31)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(41) Genomic(5) cDNA(31) Primer pair(4) Other(1) Antibodies(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000054191
DoTS DT.533967
Consensus CDS Project CCDS22483.1
UniGene 4847
DFCI TC1580465
NIA Mouse Gene Index U088097
Entrez Gene 16596
International Mouse Knockout Project Status Klf1
Protein
domains
InterPro ID Description
IPR007087 Zinc finger, C2H2-type
IPR013087 Zinc finger, C2H2-type/integrase, DNA-binding
IPR015880 Zinc finger, C2H2-like
Graphical View of Protein Domain Structure
References
(Earliest) J:1767 Attaya M et al., "Ham-2 corrects the class I antigen-processing defect in RMA-S cells." Nature 1992 Feb 13;355(6361):647-9
(Latest) J:153993 Liang SY et al., "Defective erythropoiesis in transgenic mice expressing dominant-negative upstream stimulatory factor." Mol Cell Biol 2009 Nov;29(21):5900-10
All references(50)
Other
accession IDs
MGD-MRK-9345, MGI:95311

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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