Symbol
Name
ID
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Synonyms
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Edg3, LPb3, S1P3
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Genetic Map
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Chromosome 13
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cytoband B1
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Mapping data(
3)
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(31)
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Alleles and phenotypes
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All alleles(3) :
Targeted, knock-out(3)
| Mice homozygous for disruptions in this gene display an essentially normal phenotype although litter sizes are reduced. Susceptibility to pulmonary edema is also reduced. |
Phenotype Images (5)
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Polymorphisms
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SNPs within 2kb(139 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (12 records)
Data Summary:
Assays (4)
Results (15)
Tissues (15)
Images (4)
Theiler Stages: 11,13,15,17,19,20,22
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Assay Type |
Assays |
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Results |
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RT-PCR |
2 |
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13 |
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RNA in situ |
2 |
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2 |
cDNA source data(61)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular reagents
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All nucleic(64)
cDNA(62)
Primer pair(2)
Microarray probesets(2)
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Other database links
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Protein domains
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| InterPro ID |
Description |
| IPR000276 |
7TM GPCR, rhodopsin-like |
| IPR004061 |
Sphingosine 1-phosphate receptor |
| IPR004062 |
EDG-3 sphingosine 1-phosphate receptor |
| IPR017452 |
GPCR, rhodopsin-like superfamily |
Graphical View
of Protein Domain Structure
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References
|
(Earliest)
J:52870
Zhang G et al.,
"Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate."
Gene 1999 Feb 4;227(1):89-99
(Latest)
J:148410
Combes AN et al.,
"Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development."
Dev Dyn 2009 May;238(5):1033-41
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All references(34)
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Other accession IDs
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MGI:2145186
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