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Fhl1 Gene Detail
 Symbol
Name
ID
Fhl1
four and a half LIM domains 1
MGI:1298387


Nomenclature History
Synonyms KyoT, KyoT1, KyoT2
Genetic Map
Chromosome X
cytoband A6-A7.1
 
Mapping data( 1)
Sequence Map
ChrX:53984964-54046523 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF318571
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000017580 VEGA Gene Model | MGI Sequence Detail 61560 C57BL/6J ± Kb
transcript NM_001077361 RefSeq | MGI Sequence Detail 2686 C57BL/6
polypeptide P97447 UniProt | EBI | MGI Sequence Detail 280 Not Applicable
For the selected sequences
All sequences(28)
Alleles
and
phenotypes
All alleles(2) : Targeted, other(1) Gene trapped(1)
Mice homozygous for a null allele exhibit resistance to cardiomyopathy induced by transverse aortic constriction or transgene expression.
Polymorphisms SNPs within 2kb(279 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process cell differentiation, multicellular organismal development...
Component cytoplasm, nucleus...
Function metal ion binding, zinc ion binding...
External Resources: FuncBase
Expression Literature Summary: (10 records)
Data Summary: Assays (10)    Results (173)    Tissues (152)    Images (52)
Theiler Stages: 20,21,22,24,26,28
  Assay Type Assays   Results
      RT-PCR 3   12
      RNA in situ 5   149
      Northern blot 2   12
cDNA source data(130)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(135) cDNA(132) Primer pair(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000023092
DoTS DT.101713520, DT.536644, DT.94346495, DT.97410792
Consensus CDS Project CCDS30148.1, CCDS40980.1, CCDS40981.1
UniGene 3126
DFCI TC1575023, TC1598378
NIA Mouse Gene Index U019865
Entrez Gene 14199
VEGA Gene Model OTTMUSG00000017580
International Mouse Knockout Project Status Fhl1
Protein
domains
InterPro ID Description
IPR001781 Zinc finger, LIM-type
Graphical View of Protein Domain Structure
References
(Earliest) J:49742 Kuroiwa A et al., "Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes." Cytogenet Cell Genet 1998;81(3-4):208-12
(Latest) J:156356 Cottle DL et al., "SLIMMER (FHL1B/KyoT3) interacts with the proapoptotic protein Siva-1 (CD27BP) and delays skeletal myoblast apoptosis." J Biol Chem 2009 Sep 25;284(39):26964-77
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
02/06/2010
MGI_4.32
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