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Faah Gene Detail
 Symbol
Name
ID
Faah
fatty acid amide hydrolase
MGI:109609


Nomenclature History
Genetic Map
Chromosome 4
56.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr4:115639750-115690531 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Faah ± 2 cM)
Protein SuperFamily: amidase, fungal type
TreeFam: TF314455
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000008726 VEGA Gene Model | MGI Sequence Detail 50782 C57BL/6J ± Kb
transcript NM_010173 RefSeq | MGI Sequence Detail 3816 C57BL/6
polypeptide O08914 UniProt | EBI | MGI Sequence Detail 579 Not Applicable
For the selected sequences
All sequences(44)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(2)
Mice homozygous for disruptions in this gene show a normal phenotype.
Polymorphisms PCR(1) SNPs within 2kb(128 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Component endoplasmic reticulum, Golgi apparatus...
Function carbon-nitrogen ligase activity, with glutamine as amido-N-donor, hydrolase activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (1)    Tissues (1)    Images (1)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   1
cDNA source data(72)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(75) Genomic(1) cDNA(72) Primer pair(2)
Microarray probesets(2)
Pathways
anandamide degradation
Other database
links
EC 3.5.1.n2
Ensembl Gene Model ENSMUSG00000034171
DoTS DT.101123164, DT.101123172, DT.101159327, DT.50315535, DT.55207737, DT.91316230
Consensus CDS Project CCDS18501.1
UniGene 256025
DFCI TC1574604, TC1590719, TC1608076, TC1740699
Entrez Gene 14073
VEGA Gene Model OTTMUSG00000008726
International Mouse Knockout Project Status Faah
Protein
domains
InterPro ID Description
IPR000120 Amidase
IPR015830 Amidase, fungi
IPR020556 Amidase, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:39332 Giang DK et al., "Molecular characterization of human and mouse fatty acid amide hydrolases." Proc Natl Acad Sci U S A 1997 Mar 18;94(6):2238-42
(Latest) J:154412 Wise LE et al., "Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task." Neurobiol Learn Mem 2009 Nov;92(4):597-601
All references(42)
Other
accession IDs
MGD-MRK-39608, MGI:2140571

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory