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Cmklr1 Gene Detail
 Symbol
Name
ID
Cmklr1
chemokine-like receptor 1
MGI:109603


Nomenclature History
Synonyms Gpcr27
Genetic Map
Chromosome 5
cytoband F
 
Mapping data( 2)
Sequence Map
Chr5:114062363-114100435 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: chemokine receptor-like protein CMKLR1
TreeFam: TF330976
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000025812 VEGA Gene Model | MGI Sequence Detail 38073 C57BL/6J ± Kb
transcript NM_008153 RefSeq | MGI Sequence Detail 2845 -
polypeptide P97468 UniProt | EBI | MGI Sequence Detail 371 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes
All alleles(10) : Targeted, other(1) Gene trapped(9)
Homozygous null mice have defects in immunomodulation of monocyte and neutriphils by chemerin
Polymorphisms SNPs within 2kb(186 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process G-protein coupled receptor protein signaling pathway, signal transduction...
Component integral to membrane, membrane...
Function G-protein coupled receptor activity, receptor activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (2)    Results (33)    Tissues (32)
Theiler Stages: 19,21,22,24,28
  Assay Type Assays   Results
      RNA in situ 1   32
      Northern blot 1   1
cDNA source data(5)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000042190
DoTS DT.110670456, DT.87035183
Consensus CDS Project CCDS19551.1
DFCI TC1585869
NIA Mouse Gene Index U087647
Entrez Gene 14747
VEGA Gene Model OTTMUSG00000025812
International Mouse Knockout Project Status Cmklr1
Protein
domains
InterPro ID Description
IPR000276 7TM GPCR, rhodopsin-like
IPR002258 DEZ orphan receptor
IPR017452 GPCR, rhodopsin-like superfamily
Graphical View of Protein Domain Structure
References
(Earliest) J:39842 Methner A et al., "A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development." Biochem Biophys Res Commun 1997 Apr 17;233(2):336-42
(Latest) J:133968 Cash JL et al., "Synthetic chemerin-derived peptides suppress inflammation through ChemR23." J Exp Med 2008 Apr 14;205(4):767-75
All references(8)
Other
accession IDs
MGD-MRK-39602

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory