Symbol
Name
ID
|
|
|
Synonyms
|
pantetheinase, V-1
|
|
Genetic Map
|
|
Chromosome 10
|
cytoband A1-B2
|
|
|
|
Mapping data(
4)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(19)
|
Alleles
and
phenotypes
|
All alleles(1) :
Targeted, knock-out(1)
| Mice homozygous for disruptions of this gene develop normally and so no abnormalities in the maturation of lymphoid organs. However, membrane bound pantetheinase is absent in livers and kidneys resuulting in an absence of cysteamine in these organs. |
|
|
Polymorphisms
|
SNPs within 2kb(171 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (10 records)
Data Summary:
Assays (4)
Results (60)
Tissues (24)
Images (16)
Theiler Stages: 18,20,21,22,24
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
2 |
|
46 |
| |
RNA in situ |
1 |
|
2 |
| |
Immunohistochemistry |
1 |
|
12 |
cDNA source data(24)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(28)
Genomic(1)
cDNA(24)
Primer pair(2)
Other(1)
Antibodies(1)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR003010 |
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase |
| IPR012101 |
Biotinidase, eukaryotic |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:37066
Aurrand-Lions M et al.,
"Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing."
Immunity 1996 Nov;5(5):391-405
(Latest)
J:137896
Roisin-Bouffay C et al.,
"Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes."
Diabetologia 2008 Jul;51(7):1192-1201
|
All references(26)
|
Other
accession IDs
|
MGD-MRK-37437
|
Analysis Tools
MGI BioMart