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Adm Gene Detail
 Symbol
Name
ID
Adm
adrenomedullin
MGI:108058


Nomenclature History
STS D7Wsu170e
Synonyms AM
Genetic Map
Chromosome 7
50.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 11)

Sequence Map
Chr7:117771183-117773333 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; pig, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Adm ± 2 cM)
Protein SuperFamily: adrenomedullin
TreeFam: TF333447
Sequences
Representative Sequences Length Strain/Species Flank
genomic 11535 NCBI Gene Model | MGI Sequence Detail 2151 C57BL/6J ± Kb
transcript NM_009627 RefSeq | MGI Sequence Detail 1381 C57BL/6
polypeptide P97297 UniProt | EBI | MGI Sequence Detail 184 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes
All alleles(11) : Targeted, knock-out(4) Targeted, other(3) Gene trapped(4)
Homozygotes for a targeted null mutation exhibit cardiovascular defects, hyrdops fetalis, and lethality at midgestation.
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)   Phenotype Images (5)  
Polymorphisms All PCR and RFLP(3) : PCR(1) RFLP(2) SNPs within 2kb(35 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process branching involved in embryonic placenta morphogenesis, developmental growth...
Component extracellular region
Function hormone activity
External Resources: FuncBase
Expression Literature Summary: (19 records)
Data Summary: Assays (3)    Results (18)    Tissues (12)    Images (5)
Theiler Stages: 11,15,21,24,28
  Assay Type Assays   Results
      RT-PCR 2   9
      In situ reporter (knock in) 1   9
cDNA source data(134)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(139) Genomic(1) cDNA(134) Primer pair(3) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030790
DoTS DT.533504
Consensus CDS Project CCDS21745.1
UniGene 1408
DFCI TC1575599
NIA Mouse Gene Index U008631
Entrez Gene 11535
International Mouse Knockout Project Status Adm
Protein
domains
InterPro ID Description
IPR001693 Calcitonin peptide-like
IPR001710 Adrenomedullin
Graphical View of Protein Domain Structure
References
(Earliest) J:38236 White RT et al., "Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue." J Biol Chem 1992 May 5;267(13):9210-3
(Latest) J:144528 Nagare T et al., "The Kruppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes." Biochem Biophys Res Commun 2009 Jan 30;379(1):98-103
All references(52)
Other
accession IDs
MGD-MRK-37094

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory