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Slc18a2 Gene Detail
 Symbol
Name
ID
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
MGI:106677


Nomenclature History
Synonyms 1110037L13Rik, Vmat2
Genetic Map
Chromosome 19
53.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr19:59335417-59370167 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Slc18a2 ± 2 cM)
Protein SuperFamily: synaptic vesicle amine transporter
TreeFam: TF313494
Sequences
Representative Sequences Length Strain/Species Flank
genomic 214084 NCBI Gene Model | MGI Sequence Detail 34751 C57BL/6J ± Kb
transcript NM_172523 RefSeq | MGI Sequence Detail 3803 C57BL/6
polypeptide Q8BRU6 UniProt | EBI | MGI Sequence Detail 517 Not Applicable
For the selected sequences
All sequences(19)
Alleles
and
phenotypes
All alleles(6) : Targeted, knock-out(4) Targeted, other(1) Gene trapped(1)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms RFLP(1) SNPs within 2kb(283 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process death, locomotory behavior...
Component cytoplasmic vesicle, integral to membrane...
Function protein binding
External Resources: FuncBase
Expression Literature Summary: (21 records)
Data Summary: Assays (5)    Results (105)    Tissues (98)    Images (13)
Theiler Stages: 18,22,26,28
  Assay Type Assays   Results
      Western blot 1   4
      RT-PCR 2   7
      RNA in situ 1   92
      Immunohistochemistry 1   2
cDNA source data(13)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(23) Genomic(5) cDNA(15) Primer pair(3) Antibodies(2)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000025094
Consensus CDS Project CCDS29935.1
Entrez Gene 214084
International Mouse Knockout Project Status Slc18a2
Protein
domains
InterPro ID Description
IPR011701 Major facilitator superfamily MFS-1
IPR016196 Major facilitator superfamily, general substrate transporter
Graphical View of Protein Domain Structure
References
(Earliest) J:33165 Roghani A et al., "Assignment of the mouse vesicular monoamine transporter genes, Slc18a1 and Slc18a2, to chromosomes 8 and 19 by linkage analysis." Mamm Genome 1996 May;7(5):393-4
(Latest) J:155057 Hwang DY et al., "Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons." J Neurochem 2009 Dec;111(5):1202-12
All references(57)
Other
accession IDs
MGD-MRK-35136, MGI:1916004

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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