Symbol
Name
ID
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Synonyms
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Bob-1, BOB.1, Bob1, OBF-1, OBF.1, OCA-B, OCAB
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Genetic Map
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Chromosome 9
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Syntenic
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Mapping data(
2)
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(16)
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Alleles and phenotypes
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All alleles(3) :
Targeted, knock-out(3)
| Homozygotes for targeted null mutations exhibit reduced numbers of mature B cells, absence of germinal centers, and low serum levels of non-IgM immunoglobulins. |
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Polymorphisms
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SNPs within 2kb(193 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (3 records)
Data Summary:
Assays (3)
Results (78)
Tissues (71)
Images (3)
Theiler Stages: 17,21,23,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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46 |
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RNA in situ |
2 |
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32 |
cDNA source data(30)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular reagents
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All nucleic(33)
Genomic(2)
cDNA(30)
Primer pair(1)
Microarray probesets(2)
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Other database links
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Protein domains
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| InterPro ID |
Description |
| IPR015389 |
POU, class 2, associating factor 1 |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:30126
Pfisterer P et al.,
"Functional characterization of the murine homolog of the B cell-specific coactivator BOB.1/OBF.1."
J Biol Chem 1995 Dec 15;270(50):29870-80
(Latest)
J:143921
Karnowski A et al.,
"Silencing and nuclear repositioning of the lambda5 gene locus at the pre-b cell stage requires Aiolos and OBF-1."
PLoS ONE 2008;3(10):e3568
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All references(41)
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Other accession IDs
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MGD-MRK-32126
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