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Il13ra1 Gene Detail
 Symbol
Name
ID
Il13ra1
interleukin 13 receptor, alpha 1
MGI:105052


Nomenclature History
Synonyms CD213a1
Genetic Map
Chromosome X
12.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
ChrX:33652105-33711254 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Il13ra1 ± 2 cM)
TreeFam: TF331549
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000017214 VEGA Gene Model | MGI Sequence Detail 59150 C57BL/6J ± Kb
transcript NM_133990 RefSeq | MGI Sequence Detail 3686 C57BL/6
polypeptide O09030 UniProt | EBI | MGI Sequence Detail 424 Not Applicable
For the selected sequences
All sequences(26)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(2)
Mice homozygous for a null allele exhibit enhanced Th2 response, decreased susceptibility to parasitic infection and decreased airway hyperreactivity.
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(102 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component integral to membrane, membrane...
Function cytokine receptor activity, receptor activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (2)    Results (2)    Tissues (1)
Theiler Stages: 22
  Assay Type Assays   Results
      RT-PCR 2   2
cDNA source data(31)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(35) Genomic(1) cDNA(31) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000017057
DoTS DT.101408091, DT.527701
Consensus CDS Project CCDS30057.1
UniGene 24208
DFCI TC1577689
NIA Mouse Gene Index U019774
Entrez Gene 16164
VEGA Gene Model OTTMUSG00000017214
International Mouse Knockout Project Status Il13ra1
Protein
domains
InterPro ID Description
IPR003532 Short hematopoietin receptor, family 2, conserved site
IPR003961 Fibronectin, type III
IPR008957 Fibronectin, type III-like fold
IPR015321 Interleukin-6 receptor alpha chain, binding
Graphical View of Protein Domain Structure
References
(Earliest) J:30615 Hilton DJ et al., "Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor." Proc Natl Acad Sci U S A 1996 Jan 9;93(1):497-501
(Latest) J:147719 Newcomb DC et al., "A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling attenuates Th17 cytokine production." J Immunol 2009 May 1;182(9):5317-21
All references(15)
Other
accession IDs
MGD-MRK-32091, MGI:2147937

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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