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Il1rap Gene Detail
 Symbol
Name
ID
Il1rap
interleukin 1 receptor accessory protein
MGI:104975

Nomenclature History
Synonyms 6430709H04Rik, IL-1R AcP, IL-1RAcP
Genetic Map
Chromosome 16
cytoband B2
 
Mapping data( 3)
Sequence Map
Chr16:26581854-26716652 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: interleukin-1 receptor type I
TreeFam: TF325519
Sequences
Representative Sequences Length Strain/Species Flank
genomic 16180 NCBI Gene Model | MGI Sequence Detail 134799 C57BL/6J ± Kb
transcript NM_008364 RefSeq | MGI Sequence Detail 4576 C57BL/6
polypeptide Q61730 UniProt | EBI | MGI Sequence Detail 570 Not Applicable
For the selected sequences
All sequences(41)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Polymorphisms SNPs within 2kb(912 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cytokine-mediated signaling pathway, innate immune response...
Component extracellular region, integral to membrane...
Function interleukin-1 receptor activity, protein binding...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (2)    Results (14)    Tissues (11)
Theiler Stages: 17,19,20
  Assay Type Assays   Results
      RT-PCR 2   14
cDNA source data(62)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(64) cDNA(63) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000022514
DoTS DT.101273917, DT.487163, DT.87050133, DT.91403986, DT.91554271
Consensus CDS Project CCDS28089.1
UniGene 253424
DFCI TC1579968, TC1589233, TC1597090, TC1614137, TC1614468, TC1617993
NIA Mouse Gene Index U016976
Entrez Gene 16180
International Mouse Knockout Project Status Il1rap
Protein
domains
InterPro ID Description
IPR000157 Toll-Interleukin receptor
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor, type I/II
IPR004075 Interleukin-1 receptor, type I/Toll precursor
IPR007110 Immunoglobulin-like
IPR013783 Immunoglobulin-like fold
IPR015621 Interleukin-1 receptor
Graphical View of Protein Domain Structure
References
(Earliest) J:25951 Greenfeder SA et al., "Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex." J Biol Chem 1995 Jun 9;270(23):13757-65
(Latest) J:150078 Smith DE et al., "A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1." Immunity 2009 Jun 19;30(6):817-31
All references(21)
Other
accession IDs 		MGD-MRK-31048, MGI:2146394, MGI:2146602, MGI:2441718
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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