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Lct Gene Detail
 Symbol
Name
ID
Lct
lactase
MGI:104576

Nomenclature History
Synonyms LOC226413, LPH, Lphl
Genetic Map
Chromosome 1
65.9 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr1:130181333-130224895 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; pig, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Lct ± 2 cM)
TreeFam: TF314803
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000030320 VEGA Gene Model | MGI Sequence Detail 43563 C57BL/6J ± Kb
transcript NM_001081078 RefSeq | MGI Sequence Detail 6166 -
polypeptide NP_001074547 RefSeq | MGI Sequence Detail 1931 -
For the selected sequences
All sequences(15)
Polymorphisms SNPs within 2kb(136 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process metabolic process
Function hydrolase activity, hydrolase activity, acting on glycosyl bonds...
External Resources: FuncBase
Expression Literature Summary: (3 records)
cDNA source data(15)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(16) cDNA(16)
Microarray probesets(2)
Pathways
lactose degradation III
Other database
links
Ensembl Gene Model ENSMUSG00000026354
DoTS DT.101193991
Consensus CDS Project CCDS35698.1
UniGene 26930
DFCI TC1646322
NIA Mouse Gene Index U021730
Entrez Gene 226413
VEGA Gene Model OTTMUSG00000030320
International Mouse Knockout Project Status Lct
Protein
domains
InterPro ID Description
IPR001360 Glycoside hydrolase, family 1
IPR013781 Glycoside hydrolase, subgroup, catalytic core
IPR017853 Glycoside hydrolase, catalytic core
IPR018120 Glycoside hydrolase, family 1, active site
References
(Earliest) J:29712 Uelmen PJ et al., "Tissue-specific expression and cholesterol regulation of acylcoenzyme A:cholesterol acyltransferase (ACAT) in mice. Molecular cloning of mouse ACAT cDNA, chromosomal localization, and regulation of ACAT in vivo and in vitro." J Biol Chem 1995 Nov 3;270(44):26192-201
(Latest) J:122635 Bosse T et al., "Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development." Am J Physiol Gastrointest Liver Physiol 2007 May;292(5):G1302-14
All references(9)
Other
accession IDs 		MGD-MRK-26010, MGI:1261815, MGI:2684946
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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