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Lilrb4 Gene Detail
 Symbol
Name
ID
Lilrb4
leukocyte immunoglobulin-like receptor, subfamily B, member 4
MGI:102701

Nomenclature History
Synonyms CD85K, Gp49b, HM18, ILT3
Genetic Map
Chromosome 10
32.0 cM, cytoband B4
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr10:51200446-51216419 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000016501 VEGA Gene Model | MGI Sequence Detail 15974 C57BL/6J ± Kb
transcript NM_013532 RefSeq | MGI Sequence Detail 1420 C57BL/6
polypeptide Q64281 UniProt | EBI | MGI Sequence Detail 335 Not Applicable
For the selected sequences
All sequences(15)
Alleles
and
phenotypes 		All alleles(5) : Targeted, knock-out(5)
Homozygotes for a targeted null mutation exhibit increased sensitivity to IgE-dependent passive cutaneous anaphylaxis and a reduced threshold for antigen challenge in active cutaneous anaphylaxis.
Polymorphisms RFLP(1) SNPs within 2kb(239 from dbSNP Build 128)   SNPs within 2kb including multiple locations(281)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process immune response
Component integral to membrane, membrane...
Function receptor activity
External Resources: FuncBase
Expression cDNA source data(32)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(38) Genomic(4) cDNA(34)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000062593 (also overlaps Gp49a)
Consensus CDS Project CCDS23832.1
UniGene 34408
Entrez Gene 14728
VEGA Gene Model OTTMUSG00000016501
International Mouse Knockout Project Status Lilrb4
Protein
domains
InterPro ID Description
IPR007110 Immunoglobulin-like
IPR013783 Immunoglobulin-like fold
Graphical View of Protein Domain Structure
References
(Earliest) J:17206 Castells MC et al., "Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49." J Biol Chem 1994 Mar 18;269(11):8393-401
(Latest) J:148033 Jiang L et al., "New assay to detect low-affinity interactions and characterization of leukocyte receptors for collagen including leukocyte-associated Ig-like receptor-1 (LAIR-1)." Eur J Immunol 2009 Apr;39(4):1167-75
All references(21)
Other
accession IDs 		MGD-MRK-19605
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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