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Human Disease and Mouse Model Detail
Human Disease

Term: Ciliary Dyskinesia, Primary, 3; CILD3
OMIM ID: 608644

Synonyms Ciliary Dyskinesia, Primary, 3, with or without Situs Inversus
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Dnahc5 DNAH5
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Dnahc5hlb612/Dnahc5hlb612   involves: C57BL/6J J:130755
Dnahc5Tg1Htz/Dnahc5Tg1Htz   involves: C57BL/6 * CBA/J J:76189

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory