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Human Disease and Mouse Model Detail
Human Disease

Term: Epilepsy, Nocturnal Frontal Lobe, 3; ENFL3
OMIM ID: 605375

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
     
Chrnb2 CHRNB2
  human...the human gene.
     MGI data currently do not associate this disease with mutations in the orthologous mouse gene.
     
Transgenes and
other mutation types
Tg(Prnp-tTA)F959Sbp   Characteristics of this human disease are associated with transgenes and other mutation types in mouse.
Tg(tetO-Chrnb2*V287L)H3Gica

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models involving transgenes or other mutation types.1
Tg(Prnp-tTA)F959Sbp/0
Tg(tetO-Chrnb2*V287L)H3Gica/0
  involves: 129S7/SvEvBrd * FVB J:145855

1Models involving transgenes or other mutation types may also appear in other sections of the table.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory