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Human Disease and Mouse Model Detail
Human Disease

Term: Systemic Lupus Erythematosus, Susceptibility to, 2; SLEB2
OMIM ID: 605218

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Pdcd1 PDCD1
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models
Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Pdcd1tm1Hon/Pdcd1tm1Hon   involves: 129S2/SvPas * C57BL/6 J:50688
Pdcd1tm1Hon/Pdcd1tm1Hon   B6.129S2-Pdcd1tm1Hon J:78802
Pdcd1tm1Hon/Pdcd1tm1Hon   BALB/c J:66979

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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Send questions and comments to User Support. 		last database update
04/03/2013
MGI 5.12 		The Jackson Laboratory