Human Disease and Mouse Model Detail

Human Disease

Term: Neuronal Intestinal Dysplasia, Type B
OMIM ID: 601223

Synonyms

Nid B

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene

Human Gene

Characteristics of this human disease are associated with mutations in...

Spry2	SPRY2
Tlx2	TLX2

...the mouse gene.
OMIM data currently do not associate this disease with the orthologous human gene.

Mouse Models

Genotype			Ref(s)
Allelic Composition	Note	Genetic Background
Models with phenotypic similarity to human diseases where etiology is unknown or involving genes where ortholog is unknown.¹
Spry2^tm1Ayos/Spry2^tm1Ayos		B6.Cg-Spry2^tm1Ayos	J:99827
Tlx2^tm1Htno/Tlx2^tm1Htno		involves: 129S1/Sv * 129X1/SvJ	J:42356
Tlx2^tm1Sjk/Tlx2^tm1Sjk		involves: 129/Sv * C57BL/6	J:40722

¹The causal human genes for this disease have not been identified. Genotypes may include cases where the mouse structural gene or the human ortholog has not been identified.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 04/03/2013 MGI 5.12