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Human Disease and Mouse Model Detail
Human Disease

Term: Deafness, Autosomal Recessive 7; DFNB7
OMIM ID: 600974

Synonyms Deafness, Autosomal Recessive 11; DFNB11
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Tmc1 TMC1
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models
Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Tmc1baringo/Tmc1baringo   involves: C57BL/6 J:181985
Tmc1dn/Tmc1dn   STOCK Grhl3ct/J J:236
Tmc1dn/Tmc1dn   involves: STOCK Grhl3ct * M. m. molossinus J:22445
Tmc1Mhdabth/Tmc1+   C3HeB/FeJ J:86685
Tmc1nice/Tmc1nice   involves: C57BL/6 J:181985
Tmc1stitch/Tmc1stitch   involves: C57BL/6 J:181985

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
04/03/2013
MGI 5.12 		The Jackson Laboratory