Human Disease and Mouse Model Detail

Human Disease

Term: Dubin-Johnson Syndrome; DJS
OMIM ID: 237500

Synonyms

Hyperbilirubinemia, Dubin-Johnson Type; HBLRDJ; Hyperbilirubinemia II

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene

Human Gene

Characteristics of this human disease are associated with mutations in...

Rdx

RDX

...the mouse gene.
OMIM data currently do not associate this disease with the orthologous human gene.

ABCC2

...the human gene.
MGI data currently do not associate this disease with mutations in the orthologous mouse gene.

Mouse Models

Genotype			Ref(s)
Allelic Composition	Note	Genetic Background
Models with phenotypic similarity to human disease where etiologies are distinct.¹
Rdx^tm1Sts/Rdx^tm1Sts		involves: 129S4/SvJae * C57BL/6	J:77485

¹Human genes are associated with this disease. Mouse model genotypes do not include mutations in the orthologs of these human genes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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