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Human Disease and Mouse Model Detail
Human Disease

Term: Factor X Deficiency
OMIM ID: 227600

Synonyms F10 Deficiency; Stuart-Prower Factor Deficiency
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
F10 F10
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
F10tm1Ccmt/F10tm1Ccmt   involves: 129P2/OlaHsd * C57BL/6 J:145092
F10tm1Edr/F10tm1Edr   involves: 129S1/Sv * 129X1/SvJ * Swiss J:61230
F10tm2Ccmt/F10tm2Ccmt   involves: 129P2/OlaHsd * C57BL/6 J:145092

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory