Human Disease and Mouse Model Detail

Human Disease

Term: Ectodermal Dysplasia 10b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive; ECTD10B
OMIM ID: 224900

Synonyms

Ectodermal Dysplasia, Anhidrotic; EDA; Ectodermal Dysplasia, Hypohidrotic; HED

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene

Human Gene

Characteristics of this human disease are associated with mutations in...

Edar

EDAR

...both mouse and human orthologous genes.

Mouse Models

Genotype			Ref(s)
Allelic Composition	Note	Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.¹
Edar^dl/Edar^dl		involves: A/H	J:116222
Edar^Tg(OVE1B)Ove/Edar^Tg(OVE1B)Ove		involves: C3H * C57BL/6 * FVB/N	J:56496

¹Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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