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Human Disease and Mouse Model Detail
Human Disease

Term: Diarrhea 1, Secretory Chloride, Congenital; DIAR1
OMIM ID: 214700

Synonyms Chloride Diarrhea, Congenital, Finnish Type; Chloridorrhea, Congenital
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Slc26a3 SLC26A3
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Slc26a3tm1Sole/Slc26a3tm1Sole   involves: 129S6/SvEvTac * C57BL/6 J:117587

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory