Human Disease and Mouse Model Detail

Human Disease

Term: Parietal Foramina; PFM
OMIM ID: 168500

Synonyms

Catlin Marks; Cranium Bifidum Occultum; Foramina Parietalia Permagna; FPP; Parietal Foramina, Symmetric

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene

Human Gene

Characteristics of this human disease are associated with mutations in...

Msx2

MSX2

...both mouse and human orthologous genes.

Mouse Models

Genotype			Ref(s)
Allelic Composition	Note	Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.¹
Msx2^tm1Rilm/Msx2^tm1Rilm		either: (involves: 129S4/SvJae-Msx2^tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J)	J:61509

¹Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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