Human Disease and Mouse Model Detail

Human Disease

Term: Pancreas, Annular
OMIM ID: 167750

Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene

Human Gene

Characteristics of this human disease are associated with mutations in...

Gdf1	GDF1
Ihh	IHH

...the mouse gene.
OMIM data currently do not associate this disease with the orthologous human gene.

Transgenes and
other mutation types

Dp(16Lipi-Zfp295)1Yey

Characteristics of this human disease are associated with transgenes and other mutation types in mouse.

Mouse Models

Genotype			Ref(s)
Allelic Composition	Note	Genetic Background
Models with phenotypic similarity to human diseases where etiology is unknown or involving genes where ortholog is unknown.¹
Gdf1^tm1Sjl/Gdf1^tm1Sjl		involves: 129S1/Sv * 129X1/SvJ * C57BL/6	J:60755
Ihh^tm1Amc/Ihh^tm1Amc		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J	J:62158
Models involving transgenes or other mutation types.²
Dp(16Lipi-Zfp295)1Yey/0		involves: 129S7/SvEvBrd	J:121790

¹The causal human genes for this disease have not been identified. Genotypes may include cases where the mouse structural gene or the human ortholog has not been identified.
²Models involving transgenes or other mutation types may also appear in other sections of the table.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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