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Human Disease and Mouse Model Detail
Human Disease

Term: Neuropathy, Hereditary, with Liability to Pressure Palsies; HNPP
OMIM ID: 162500

Synonyms Polyneuropathy, Familial Recurrent; Tomaculous Neuropathy
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Pmp22 PMP22
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Pmp22tm1Lnot/Pmp22+   Not Specified J:104989
Pmp22tm1Ueli/Pmp22tm1Ueli   involves: 129S/SvEv J:29517

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory