About   Help   FAQ
Human Disease and Mouse Model Detail
Human Disease

Term: Muscular Dystrophy, Limb-Girdle, Type 1B; LGMD1B
OMIM ID: 159001

Synonyms Muscular Dystrophy, Proximal, Type 1B
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
     
Zmpste24 ZMPSTE24
  mouse...the mouse gene.
     OMIM data currently do not associate this disease with the orthologous human gene.
     
Lmna LMNA
  human...the human gene.
     MGI data currently do not associate this disease with mutations in the orthologous mouse gene.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies are distinct.1
Zmpste24tm1Lotn/Zmpste24tm1Lotn   involves: 129P2/Ola * C57BL/6 J:76209

1Human genes are associated with this disease. Mouse model genotypes do not include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/03/2013
MGI 5.12
The Jackson Laboratory