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Human Disease and Mouse Model Detail
Human Disease

Term: Fundus Dystrophy, Pseudoinflammatory, of Sorsby; SFD
OMIM ID: 136900

Synonyms Macular Dystrophy, Hemorrhagic
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Timp3 TIMP3
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Timp3tm1Web/Timp3+   either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) J:78059
Timp3tm1Web/Timp3tm1Web   either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) J:78059

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory