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Human Disease and Mouse Model Detail
Human Disease

Term: Cataract, Zonular Pulverulent 1; CZP1
OMIM ID: 116200

Synonyms CAE1; Cataract, Duffy-Linked; Pulverulent Zonular Cataract
Associated Genes

Orthologous mouse and human markers where mutations in one or both species have been associated with phenotypes characteristic of this disease.

Mouse Gene
Human Gene
 
Characteristics of this human disease are associated with mutations in...
Gja8 GJA8
  mousehuman...both mouse and human orthologous genes.
     

Mouse Models

Genotype Ref(s)
Allelic Composition Note Genetic Background
Models with phenotypic similarity to human disease where etiologies involve orthologs.1
Gja8No2/Gja8+   involves: 101 * C3H J:49492
Gja8No2/Gja8No2   involves: 101 * C3H J:49492
Gja8tm1Paul/Gja8tm1Paul   involves: 129S4/SvJae * C57BL/6J J:50894

1Human genes are associated with this disease. Mouse model genotypes include mutations in the orthologs of these human genes.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/03/2013
MGI 5.12
The Jackson Laboratory