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| Nomenclature |
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Symbol:
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Lmx1adr
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Name:
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LIM homeobox transcription factor 1 alpha;
dreher
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MGI ID: |
MGI:1856494 |
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Synonyms: |
dr |
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Gene:
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Lmx1a
Location:
Chr1:169619370-169778872 bp, + strand
Genetic Position: Chr1,
88.2 cM
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Mutation
origin |
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Mutation
description |
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Allele
Type: |
Spontaneous |
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Mutation: |
Single point mutation |
| |
An A to T transversion in exon 2 resulted in an aspartate to valine substitution at amino acid 44. (J:60593, J:115043) |
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Inheritance: |
Recessive |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lmx1a Mutation:
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4 strains or lines available |
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Phenotype
summary
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Phenotype Summary by Mammalian Phenotype terms
(show or
hide all annotated terms)
Genotypes are listed in the next section.
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Key:
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| hm |
homozygous |
ht |
heterozygous |
| cn |
conditional genotype |
cx |
complex: > 1 genome feature |
| tg |
involves transgenes |
ot |
other: hemizygous, indeterminate,... |
| N |
normal phenotype |
 |
expected model not found |
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Phenotypic
data by
genotype
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Phenotypic Data by Genotype
(show or
hide all phenotypic details)
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| Genotype | Allelic Composition | Genetic Background |
|
  hm1
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Lmx1adr/Lmx1adr |
Not Specified |
behavior/neurological hearing/vestibular/ear pigmentation skin/coat/nails nervous system embryogenesis |
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Notes |
This allele was discovered in a litter of wild mice captured in a factory in Detmold Germany.
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| References |
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Original: |
J:15346
FALCONER DS et al.,
"[Dreher, a new gene of the waltzer-shaker group in the house mouse.]"
Z Indukt Abstamm Vererbungsl 1951;84(2):71-3
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All: |
11 reference(s)
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