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| Nomenclature |
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Symbol:
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Tg(Wap-Tsg101)4389Kuw
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Name:
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transgene insertion 4389, Kay-Uwe Wagner
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MGI ID: |
MGI:3710126 |
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Transgene:
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Tg(Wap-Tsg101)4389Kuw
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: An HA-tagged Tsg101 cDNA was cloned into the blunted Asp718 and SalI sites of a WAP-based mammary specific expression vector replacing exons 1-3 of WAP. Expression of Tsg101 is thus under the control of the WAP promoter. (J:121475)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:121475
Oh KB et al.,
"Tsg101 is upregulated in a subset of invasive human breast cancers and its targeted overexpression in transgenic mice reveals weak oncogenic properties for mammary cancer initiation."
Oncogene 2007 Aug 30;26(40):5950-9
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All: |
1 reference(s)
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Analysis Tools
