Adam21tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Adam21tm1Dgen
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Name:
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a disintegrin and metallopeptidase domain 21;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3663320 |
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Gene:
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Adam21
Location:
Chr12:81558584-81568474 bp, - strand
Genetic Position: Chr12,
37.79 cM
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Mutation origin |
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Mutant Cell Line:
| 7990 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details:
A LacZ-neomycin cassette was inserted into the gene so that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts were detected in most tissues tested but not in heart, thymus, bone marrow, and urinary bladder. LacZ expression was detected in kidney and testis tissues. No LacZ expression was detected in nervous, cardiovascular, hematopoietic tissue, the respiratory system, liver, pancreas, urinary bladder, thyroid, pituitary, adrenal, prostate glands, skeletal muscle, skin, ovary, uterus, or cervix. (J:101679)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
1 reference(s)
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