Gabra4tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Gabra4tm1Dgen
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Name:
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gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604588 |
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Gene:
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Gabra4
Location:
Chr5:71569734-71658308 bp, - strand
Genetic Position: Chr5,
38.08 cM
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Mutation
origin |
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Mutant Cell Line:
| 3066 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the brain, cortex, subcortical region, cerebellum, olfactory bulb, pancreas and pituitary gland and lower levels in brainstem, spinal cord, eye, Harderian glands, lung, kidney, spleen, lymph nodes, skin, urinary bladder, adrenal gland, salivary gland, tongue, stomach, small intestine, testis, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. Beta-galactosidase expression from this allele is detectable in brain, spinal cord, pancreas, pituitary gland and salivary glands.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
1 reference(s)
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Analysis Tools
