Gpr151tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Gpr151tm1Dgen
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Name:
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G protein-coupled receptor 151;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604578 |
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Gene:
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Gpr151
Location:
Chr18:42578020-42579652 bp, - strand
Genetic Position: Chr18,
22.71 cM
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Mutation
origin |
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Mutant Cell Line:
| 7935 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the lymph nodes, moderate levels in cerebellum, olfactory bulb, spinal cord, Harderian glands, lung, liver, pancreas, skin, urinary bladder, pituitary gland, adrenal gland, tongue, stomach, small intestine, epididymis, coagulating gland, prostate gland, ovary and uterus and low levels in whole brain, cortex, subcortical region, brainstem, eye, heart, kidney, spleen, thymus, bone marrow, gallbladder, salivary gland, large intestine, cecum, testis, seminal vesicle and white fat. Beta-galactosidase expression from this allele is detectable only in brain. In the whole mount brain, moderate staining was observed in the thalamus and cerebellum with weak staining in the brainstem. On coronal sections, faint expression was detected in a few cells in the Purkinje cell layer of the cerebellum.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
1 reference(s)
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Analysis Tools
