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| Nomenclature |
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Symbol:
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Scn11atm1Dgen
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Name:
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sodium channel, voltage-gated, type XI, alpha;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604572 |
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Synonyms: |
Nav1.9-, SCN11A- |
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Gene:
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Scn11a
Location:
Chr9:119753763-119825456 bp, - strand
Genetic Position: Chr9,
71.33 cM, cytoband F3-F4
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Mutation origin |
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Mutant Cell Line:
| 3268 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An IRES-lacZ-neo cassette was inserted to replace 174 bp encompassing exon 3 and parts of exons 2 and 4, and encoding the first and second membrane-spanning segments of domain I. While RT-PCR analysis detects a gene transcript in most tissues analyzed, beta-galactosidase expression from this allele is not detectable in any tissues or organs. (J:99870)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
4 reference(s)
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