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| Nomenclature |
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Symbol:
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Tgfbr1tm1Dgen
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Name:
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transforming growth factor, beta receptor I;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604556 |
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Gene:
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Tgfbr1
Location:
Chr4:47353222-47414931 bp, + strand
Genetic Position: Chr4,
26.02 cM
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Mutation origin |
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Mutant Cell Line:
| 4398 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in most tissues analyzed, beta-galactosidase expression from this allele is detectable in all organs examined, with most striking expression in aorta and other blood vessels, heart valve, renal papilla, muscularis of the urinary bladder, corpus lutea in the ovary and in testis.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
1 reference(s)
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