Faim2tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Faim2tm1Dgen
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Name:
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Fas apoptotic inhibitory molecule 2;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604553 |
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Synonyms: |
LFG KO |
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Gene:
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Faim2
Location:
Chr15:99497005-99528017 bp, - strand
Genetic Position: Chr15,
56.13 cM, cytoband F3
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Mutation origin |
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Mutant Cell Line:
| 3150 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects gene transcript in brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, heart, lung, pancreas, kidney, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, large intestine, cecum, testis, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. Beta-galactosidase expression from this allele is detectable in brain. In wholemount staining lacZ expression is detectable in olfactory bulb, cortex, thalamus, hypothalamus and cerebellum. On coronal sections lacZ expression is detectable in cortex and hippocampus.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
2 reference(s)
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