S1pr4tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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S1pr4tm1Dgen
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Name:
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sphingosine-1-phosphate receptor 4;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604550 |
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Gene:
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S1pr4
Location:
Chr10:81497745-81500132 bp, - strand
Genetic Position: Chr10,
39.72 cM, cytoband C1
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Mutation
origin |
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Mutant Cell Line:
| 3620 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in spleen and lymph nodes, moderate levels in lung, thymus, bone marrow, gallbladder, pituitary gland, uterus and white fat and low levels in brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, Harderian glands, heart, liver, kidney, skin, urinary bladder, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, large intestine, cecum, testis, epididymis, coagulating gland, prostate gland and ovaries. However, beta-galactosidase expression from this allele is detectable only in testis with strong staining in several spermatogenic cells in the seminiferous tubules of testis.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
2 reference(s)
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Analysis Tools
