Drd5tm1Dgen
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Drd5tm1Dgen
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Name:
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dopamine receptor D5;
targeted mutation 1, Deltagen
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MGI ID: |
MGI:3604549 |
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Gene:
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Drd5
Location:
Chr5:38319509-38322310 bp, + strand
Genetic Position: Chr5,
20.4 cM
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Mutation
origin |
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Mutant Cell Line:
| 1853 (Deltagen) |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101679
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in whole brain, cortex, subcortical region, brainstem, olfactory bulb, spinal cord, eye, spleen and testis and low levels in cerebellum, thymus, skin, urinary bladder, pituitary gland, epididymis, coagulating gland, prostate gland, and white fat. However, beta-galactosidase expression from this allele is faintly detectable in only in a few follicles in the ovary. (J:101679)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
See also,
data
as provided by Deltagen, Inc.
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| References |
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Original: |
J:101679
Deltagen Inc,
"NIH initiative supporting placement of Deltagen, Inc. mice into public repositories"
MGI Direct Data Submission 2005;():
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All: |
2 reference(s)
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Analysis Tools
